Comments on the paper by Nielsen et al. entitled “Intraoperative S‐ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid‐dependent patients”

Abstract

After reading the article(Nielsen et al., 2019) presented in the latest issue, we reviewed another related article(Nielsen et al., 2017) published by the same author in 2017. The two articles were based on the same clinical trial (NCT02085577) assessing the effect of intraoperative ketamine on opioid consumption and pain after spine surgery in opioid‐dependent patients. In the earlier article, authors found that morphine consumption, both perioperatively and at 6 months after surgery, was reduced in the ketamine group compared with the placebo group.

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