Thursday, March 21, 2019

Associations Between Catecholaminergic and Serotonergic Genes and Persistent Arm Pain Severity Following Breast Cancer Surgery

Surgery is the primary treatment for breast cancer. Unfortunately, 25% to 60% of patients will report persistent postsurgical pain following breast cancer surgery.2,19 This pain usually occurs about twelve weeks post-surgery and is characterized by burning, throbbing, or aching in the ipsilateral chest, axilla, and/or arm. This pain is associated with other breast and arm symptoms, including swelling and weakness. While previous studies have identified various demographic and clinical risk factors,1,5,31,40,42,57 as well as physiological factors (e.g., genetic variations9,32,39,64) associated with the development of persistent pain following breast cancer surgery, its exact etiology remains elusive.

from The Journal of Pain https://ift.tt/2HQFcc1
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