Sudden onset diffuse erythema and oedema of the breast

A 40 year old premenopausal white woman presented to a general gynaecologist with diffuse redness, swelling, and rapidly progressive pain in her left breast. She did not have a fever. Her medical history included one full term pregnancy with spontaneous delivery 19 years earlier. Her maternal grandmother had died of breast cancer at age 65 years. On physical examination, a warm and painful diffuse oedematous erythema was found in the inner quadrants of the breast (fig 1), but she was otherwise in good general health.bmj;351/aug06_2/h4166/FIG1F1fig1Questions1. On the basis of the history and examination findings, what are the differential diagnoses and the probable diagnosis?2. What investigation(s) would you undertake to confirm your diagnosis?3. What is the optimal treatment for this condition?Answers1. On the basis of the history and examination findings, what are the differential diagnoses and the probable diagnosis?Short answerNon-lactational mastitis, cellulitis, abscess, and inflammatory breast cancer (IBC). Figure 1 shows...

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