Familial amyloid polyneuropathy (FAP) due to transthyretin (TTR) mutation is small fiber predominant polyneuropathy, exposing patients with TTR-FAP to develop neuropathic pain. However, the question of the painful nature of TTR-FAP has never been specifically addressed. In this study, we compared two groups of 16 patients with either painless or painful TTR-FAP regarding various clinical and neurophysiological variables, including laser evoked potential (LEP) recording and quantitative sensory testing.
from The Journal of Pain http://ift.tt/1gS4oh1
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