Evidence for sustained mechanical pain sensitization in women with chronic temporomandibular disorder versus healthy female participants

Generalized dysfunction of the nociceptive system has been hypothesized as an important pathophysiological process underlying TMD pain. To date, studies have not identified sensitization among TMD participants with chronic pain to painful stimuli administered prospectively across consecutive days. We attempted to isolate an empirically derived laboratory-based marker of sustained mechanical pain sensitization. We examined whether this index accounted for variance in prospective assessments of clinical TMD pain.

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