The effect of variation on the basal pain sensitivity in the general population: an experimental study in young women

SCN9A is a key player in various rare monogenic pain disorders, including absence of pain or extreme pain, indicating that SCN9A is critical in human pain perception. This study aimed to investgate the association between the single-nucleotide polymorphisms (SNPs) in SCN9A and basal pain sensitivity variability in the general population. In the present study, we used a combined tag and candidate SNP approach to explore possible associations between SCN9A SNPs and basal pain sensitivity in 309 Chinese healthy female undergraduates.

from The Journal of Pain http://ift.tt/1UM6yOZ
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