Nature Neuroscience 18, 1059 (2015). doi:10.1038/nn.4057
Authors: Victoria E Brings & Mark J Zylka
A study finds that pain hypersensitivity in male and female mice is differentially dependent on microglia and T cells, and describes a sex-specific response to microglia-targeted pain treatments. This sex difference will be important to consider when developing treatments for pain and other neurological disorders involving microglia and immune cells.
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