Arthritis is a common cause of chronic musculoskeletal pain and disability; especially across ageing populations. Arthritis has traditionally been classified as either inflammatory (e.g. rheumatoid arthritis; RA) or non-inflammatory (e.g. osteoarthritis; OA, the commonest reason for joint replacement surgery). RA is a systemic, autoimmune condition with a predilection for synovial joints of the hands and feet. Synovitis (inflammation of the joint lining) contributes to pain, and also leads to joint damage.
from The Journal of Pain http://bit.ly/2QQTNVm
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