Neuropathic pain develops in response to injuries or diseases which affect the somatosensory nervous system.31 The symptoms include hyperalgesia and allodynia, which are defined as increased responsiveness to painful stimuli and painful response to non-noxious stimuli.79 Morphine, as a powerful analgesic drug, is commonly used to alleviate different types of pain.46 Due to the development of tolerance, dependence and addiction following morphine administration,55 it seems that combination of morphine with other drugs may be a strategy to potentiate the effect of its low doses without producing the serious side effects associated with pain treatment.
from The Journal of Pain http://bit.ly/2ScIlZe
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