Distinct thalamocortical circuits underlie allodynia induced by tissue injury and by depression-like states

Nature Neuroscience, Published online: 08 March 2021; doi:10.1038/s41593-021-00811-x

Pain hypersensitivity can result from tissue injury and from depression. This study in mice shows that distinct thalamocortical pathways mediate allodynia associated with injury and a stress-induced depression-like state, respectively.

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