Abstract
Background and Objective
Having to deal on a daily routine with prescriptions in adults with intellectual disability (ID), we systematically reviewed the literature on the specificities of pain interventions in that population, focusing on medication and trying to gather practical information on appropriate pain treatments. Given the scarcity of the literature on the topic, we also discussed the pharmacological considerations to be taken into account when prescribing analgesic drugs in that vulnerable population.
Databases and Data Treatment
Articles on pain and intellectual disability were searched in the Medline and Google scholar electronic databases using the key words "Intellectual Disability", "Developmental Disability" and specific keywords for pharmacological and non‐pharmacological pain interventions. Preset outcomes about pharmacological treatment specificity, efficacy and safety were then collected.
Results
One hundred and fifty‐two articles were found and 16 were retained based on our inclusion and exclusion criteria. Of the 16 articles, 5 were topical reviews. Amongthe 11 remaining articles, 5 discussed pharmacological interventions, 4 considered non‐pharmacological interventions and 2 discussed both. As anticipated, the literature matching our specific outcomes about the pharmacological treatment of pain was scarce and and for the most part not designed to answer the questions of specificity, efficacy and safety of pain treatment in adults with ID.
Conclusion
The specificity of analgesic treatments in adults with ID is a totally unexplored domain. In the absence of clinical guidelines, pharmacological facts ‐ such as inter‐individual variability in drug response, pharmacokinetic and pharmacodynamic interactions, frequent comorbidities and ease of administration ‐ must be systematically integrated, when prescribing in the population of adults with ID.
from Wiley: European Journal of Pain: Table of Contents https://ift.tt/31XWsnK
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