• Stress induced visceral hypersensitivity in male and female Sprague-Dawley rats• The hypersensitivity persisted several weeks in females, a few days in males• Ovariectomy blocked and orchiectomy facilitated the hypersensitivity• E2 in males increased hypersensitivity, testosterone in females decreased it• E2 and testosterone altered glutamatergic receptor expression in the dorsal horn
from The Journal of Pain http://ift.tt/2GMznIG
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