Stimulation-evoked antinociception (SEA) from the anterior pretectal nucleus (APtN) activates mechanisms that descend to the spinal cord through the dorsolateral funiculus, but the encephalic route followed by the descending pathways from the APtN is not completely known.This study evaluates the changes in the SEA from the APtN in the Wistar rat tail-flick test following lidocaine-induced neural block or NMDA-induced neurotoxic lesion of the deep mesencephalic nucleus (DpMe), tegmental pedunculopontine nucleus (PPTg), or lateral paragigantocellular nucleus (LPGi).
from The Journal of Pain http://ift.tt/2aPbeFn
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