Interventions developed to improve disability outcomes for low back pain (LBP) often show only small effects. Mediation analysis was used to investigate what led to the effectiveness of the STarT Back trial, a large primary care-based trial which treated patients consulting with LBP according to their risk of a poor outcome. The high-risk subgroup, randomised to receive either psychologically-informed physiotherapy (n=93) or current best care (n=45), were investigated to explore pain-related distress and pain intensity as potential mediators of the relationship between treatment allocation and change in disability.
from The Journal of Pain http://ift.tt/2bM0CUW
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