Refractory to most types of treatment, neuropathic pain (NP) is a major problem for people living with spinal cord injury (SCI). Among problems related to treatment, underlying mechanisms are poorly understood. The aim of the present study was to investigate the association between cortical reorganization and NP after SCI. 24 individuals with sensorimotor complete and incomplete para- and tetraplegia (12 suffering from NP, 13 pain-free) and 31 healthy subjects were examined. Functional magnetic resonance imaging was used to assess activation in primary somatosensory and motor cortices in response to motor (i.e., active and passive wrist extension) and sensory (i.e., heat and brushing) tasks applied on the dorsum of the hand.
from The Journal of Pain http://ift.tt/1V0OnlY
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