Pain is defined as an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage.62 Pain sensation is considered indispensable to survival, leading to the protective behavior necessary to enable injured tissues to heal.1 It is a major symptom of many medical conditions and can interfere with a person's quality of life and general functioning.2, 6 The mechanism and regulation of pain includes the operation of noxious stimulus to pain receptors and their process and conduction to the central nervous system.
from The Journal of Pain https://ift.tt/3h8rgtA
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