Musculoskeletal diseases are highly prevalent in the general population and are a leading cause of disability among patients and medical costs every year.5,21,32,34,44,58 Diseases affecting bone and their (surgical) treatment can lead to considerable pain.18 Bone pain negatively affects mobility, inhibits rehabilitation, and can lead to long-term disabilities.12,13,42,50,53,62,63 The complex underlying mechanisms and multiple possible etiologies of bone pain, make this pain difficult to attenuate.
from The Journal of Pain https://ift.tt/2RuTN3K
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