Osteoarthritis (OA) affects 32.5 million individuals and is among the leading causes of pain and disability in the United States, with annual direct (i.e., medical expenditure) and indirect (i.e., loss earnings) costs estimated at $16,000 per patient and an annual societal economic impact of $486 billion.134 OA is a significant cause of musculoskeletal pain, stiffness, swelling, and restricted range of motion,37 and adversely impacts mobility,15 activities of daily living,127 quality of life,2 and psychological functioning.
from The Journal of Pain https://ift.tt/2G7SjGp
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