Design and reporting characteristics of clinical trials of select chronic and recurrent pediatric pain conditions: An ACTTION systematic review

Chronic and recurrent pain are common in the pediatric population, with median prevalences ranging from 11-38% reported in the literature depending on the type of pain and criteria used to define chronic and recurrent pain.25 However, a paucity of clinical trials is available that provide adequate evidence to inform pediatric pain management and evidence-based treatment guidelines.13 Many of the current pediatric pain treatment recommendations, therefore, rely on efficacy data extrapolated from studies that included only adults.

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