Friday, November 27, 2020

Transcranial direct current stimulation of the dorsolateral prefrontal cortex alters emotional modulation of spinal nociception

Emotion has a strong modulatory effect on pain perception and the nociceptive system 8,42,43. In healthy individuals, experience of unpleasant emotions facilitates pain, whereas experience of pleasant emotions inhibits pain 43. Dysregulation of this system has been identified in clinical populations and has been theorized as a mechanism underlying development and maintenance of chronic pain 8,12,17,38,49. However, experimental evidence for the neural mechanisms involved in these processes is limited 46.

from The Journal of Pain https://ift.tt/3lcfizd
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