The use of biomarkers as an objective measure of pain has received substantial attention in the recent literature, with proponents arguing that brain-derived markers in particular may some day surpass, or even replace, self-report in the characterization of pain.1 Several empirical studies regarding the use of pain biomarkers for diagnosis and classification have been published in recent years.3,7,14,22 However, to our knowledge, no such studies have considered the critical effect of previous probabilities on the diagnostic utility of biomarkers for pain.
from The Journal of Pain http://ift.tt/1RWeut7
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