Dysmenorrhea, or painful menstrual cramps, is the most common gynecological condition among women of reproductive age,13 with severe dysmenorrhea affecting 2%-29% of menstruating women.36 Dysmenorrhea is associated with significant academic impact worldwide,1 and has been identified as the leading cause of lost work hours for women in the United State (US).18 Despite substantially decreasing women's physical and psychosocial well-being,63 dysmenorrhea is undertreated and its etiology and long-term impact understudied.
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