Cytotoxic chemotherapy is the oldest and most used cancer treatment modality. This group of compounds lack selectivity to cancer cells, leading to several well-known side effects to healthy tissues 27,67. Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a cytotoxic and dose-limiting effect caused by some drugs - such as oxaliplatin (OXA), paclitaxel, bortezomib and Vinca alkaloids - which has been reported as the most frequent neurological complication of chemotherapy 27,67. CIPN is characterized by paresthesia, dysesthesia and numbness in hands and feet, associated with neuropathic pain in the most severe cases 61,67.
from The Journal of Pain https://ift.tt/3sgTRBx
via IFTTT
No comments:
Post a Comment