A cost-effectiveness analysis of an internet-delivered pain management program delivered with different levels of clinician support: Results from a randomised controlled trial.

Chronic pain significantly affects the lives of approximately 1 in 20 adults37 and is associated with increased risk of mental health difficulties, such as anxiety and depression30,32. The economic costs of chronic pain are also significant in terms of both lost workforce participation and ongoing health care use2,39. Reflecting this, in 2012, chronic pain was estimated to cost up to $635 billion every year in the United States18.

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