Opioids are commonly prescribed for postoperative pain77 or severe neuropathic pain.75 However, many patients continue to consume opioids well after surgery21 due to continued pain18 or postsurgical opioid over-prescription.5, 40 Analgesic tolerance developing after repeated opioid consumption7 further increases the risk of developing opioid dependence, withdrawal and/or overdose.38, 68 Therefore, unresolved severe chronic pain or opioid over-prescription may lead to opioid use disorder,22, 23 contributing to the ongoing opioid crisis.
from The Journal of Pain https://ift.tt/319XhKO
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