Investigating the true effect of psychological variables measured prior to arthroplastic surgery on post-surgical outcomes: a p-curve analysis

Osteoarthritis (OA) is a chronic pain condition that affects roughly 8.75 million people in the UK, with the knee and hip being the most commonly affected sites 2. Although arthroplasty is considered an effective treatment and, in many cases, a cure for chronic OA-pain, almost 30% of patients undergoing knee or hip replacement surgery develop increased pain and disability, despite objective indicators of surgical success 7,17,51. Patients’ pre-surgical psychological profiles may play a major role in determining the long-term efficacy of surgery by affecting the recovery process 13,32,40,45,59,60,68,78–80.

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