Maternal diaphragmatic hernia in mid-pregnancy

A 34 year old woman at 25 weeks’ gestation presented to the emergency department with chest pain. A chest radiograph revealed a haemopneumothorax-like air-fluid interface and absent lung markings in...

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Traumatic knee pain in a child

A 12 year old boy presented to the emergency department with his parents after falling from a motocross bike. The child was unable to describe the precise history of the event or injury mechanism,...

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Acupuncture Resolves Persistent Pain and Neuroinflammation in a Mouse Model of Chronic Overlapping Pain Conditions

Chronic overlapping pain conditions (COPCs), such as fibromyalgia (FM), temporomandibular disorder (TMD), episodic migraine (EM), tension-type headache (TTH), and low back pain (LBP) affect over 100 million Americans and costs the US economy billions of dollars each year22. A hallmark of the COPCs is their idiopathic pathogenesis20. Each individual condition produces pain unexplained by clinical findings such as injury or inflammation97. Furthermore, each is characterized by pain that persists “beyond the normal time of healing”, thereby meeting the IASP definition of chronicity67.

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The Effects of Neck-Specific Training versus Prescribed Physical Activity on Pain and Disability in Patients with Cervical Radiculopathy: A Randomized Clinical Trial

Brain mechanisms of anticipated painful movements and their modulation by Manual Therapy in chronic Low Back Pain

Heightened anticipation and fear of movement-related pain has been linked to detrimental fear-avoidance behavior in chronic Low-Back Pain (cLBP). Spinal Manipulative Therapy (SMT) has been proposed to work partly by exposing patients to non-harmful but forceful mobilization of the painful joint, thereby disrupting the relationship between pain anticipation, fear, and movement. Here, we investigated the brain processes underpinning pain anticipation and fear of movement in cLBP, and their modulation by SMT, using functional Magnetic Resonance Imaging.

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Michael Rosen: anaesthetist who championed patients’ rights to pain relief

bmj;362/jul03_9/k2894/FAF1faMichael Rosen was a pioneering anaesthetist who championed patients’ rights to pain relief and fought for his profession to receive proper recognition. Determined to show...

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Combination drug therapy for the management of low back pain and sciatica; systematic review and meta-analysis

Low back pain is a highly prevalent condition, causing considerable disability and burden globally19. Up to 70% of people will experience low back pain during their lifetime54. Patients with low back-related leg pain, such as sciatica, experience intense radiating leg pain that may be accompanied by neurological signs20 and both low back pain and sciatica are associated with high healthcare costs, work absenteeism and economic burden19,53.

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