A 42-year-old woman with a sudden onset of abdominal pain requested to see us urgently. 5 years earlier she had been diagnosed with paroxysmal nocturnal haemoglobinuria (PNH) and had missed multiple follow-up appointments. Despite having a large PNH clone—greater than 50% of PNH granulocytes—the patient had been asymptomatic with only mildly elevated haemolytic parameters and treatment with eculizumab had been deferred.
from The Lancet https://ift.tt/2Xdi2GL
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