Shoulder surgery has become a primary intervention for treating persistent shoulder pain, with the number of procedures now exceeding 500,000 annually.26 However, many patients who undergo shoulder surgery experience persistent post-operative pain.3,35 For musculoskeletal pain conditions, current research initiatives aim to identify phenotypical characteristics that predict variability in treatment outcomes.4,12 Our team used exercised-induced shoulder pain to identify an interaction between psychological distress (pain catastrophizing) and genetics (catechol-O-methyltransferase (COMT) enzyme activity) that predicted elevated pain and disability.
from The Journal of Pain https://ift.tt/367ayV1
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