Pediatric Patient-Reported Outcomes Measurement Information System is Equivalent to Scoliosis Research Society-22 in Assessing Health Status in Adolescent Idiopathic Scoliosis

Study Design. This was a correlational study. Objective. Determine the range of pediatric Patient-Reported Outcomes Measurement Information System (PROMIS) scores for patients treated for adolescent idiopathic scoliosis (AIS) and assess correlation with Scoliosis Research Society-22 (SRS-22) domain scores. Summary of Background Data. Patient reported outcome (PRO) measures are important metrics for measuring health status in diverse patient populations. PROMIS is increasingly being used in orthopedic practice. Existing literature compares PROMIS measures favorably to legacy measures in numerous adult orthopedic conditions. This study sought to define the range of PROMIS mobility, pain interference, and peer relationships scores for adolescents treated for AIS. Furthermore, correlations between these domains and equivalent domains in the legacy PRO, SRS-22, were determined. Methods. Pediatric PROMIS and SRS-22 were obtained at routine clinical visits for AIS at a tertiary care children's hospital from January 2017 to October 2017. Spearman correlations were performed to examine the associations between three pediatric PROMIS domains and the SRS-22 domains. Only patients who completed both PRO measures were included in the analyses. Radiographic measurements were performed at each visit assessing sagittal and coronal deformity and overall spinal balance. Results. One hundred thirteen patients with a mean age of 14.4 (standard deviation [SD] = 2.1) years completed the assessments. The mean pediatric PROMIS domain scores included: mobility 50.9 (interquartile range [IQR] 36.2–65.6); pain interference 45.9 (IQR 28.9–62.9); peer relations 52.6 (IQR 38.3–64.9). PROMIS mobility was strongly correlated with SRS-22 function (r = 0.65; P <� 0.001). PROMIS pain interference was strongly correlated with SRS-22 pain (r = 0.70; P <� 0.001). PROMIS peer relations was moderately correlated with SRS-22 Mental Health (r = 0.41; P <� 0.001) and self-image (r = 0.34; P <� 0.001). Conclusion. In AIS patients pediatric PROMIS pain interference and mobility correlate strongly with SRS-22 pain and function domains, while PROMIS peer relationships demonstrates moderate correlations with SRS-22 mental health and self-image. Level of Evidence: 2

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