It is well established in healthy humans that marked changes in brain rhythmic oscillatory activity over a wide range of frequency bands are related to pain processing.30,32 This also applies for head pain associated to migraine. Several electrophysiological studies have shown that migraine is a brain disorder characterized by an abnormal cortico-subcortical oscillatory activity that fluctuates along the migraine cycle, differs between the ictal and inter-ictal intervals,7,12,34,35,46 and remains persistently altered as the disease chronifies.
from The Journal of Pain https://ift.tt/30PD4Hm
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