Pain after Spinal Cord Injury is Associated with Abnormal Presynaptic Inhibition in the Posterior Nucleus of Thalamus

• Electrolytic lesion of STT produces behavioral signs consistent with SCI-Pain.• Tonic activation of presynaptic GABAB autoreceptors in PO is absent in SCI-Pain.• Regulation of glutamatergic release in PO by GABABR is absent in SCI-Pain.

from The Journal of Pain http://ift.tt/2FtjSpM
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