Abstract
Background
Pain remains a prevalent symptom for rheumatoid arthritis (RA) patients despite a wide therapeutic choice. The objective of this study was to provide a multidimensional evaluation of pain.
Methods
295 RA patients from 7 French rheumatology centers were enrolled in a cross‐sectional study. Patients completed a chronic pain assessment questionnaire approved by the French National Authority for Health, the health assessment questionnaire (HAQ), as well as depression and anxiety scales (HAD, Beck Depression Inventory, STAI). Disease activity (DAS28) and ESR were recorded. A multi‐variate descriptive analysis was undertaken using principal component analysis (PCA)
Results
38.4% of patients had a pain score > 40 mm/100 although 83% were on biological treatment and 38.7 % were in remission based on the RA activity score. The PCA analysis found 4 axes representing 70% of total variance. The axes, percent of variance and variables represented were: (1) axis 1, 41% variance, anxiety and depression scores, sensory and affective qualifier score, HAQ and pain impact on daily life; (2) axis 2, 13% variance, disease activity score (DAS28) and pain relief with current treatment; (3) axis 3, 9% of variance, RA duration and radiographic score, (4) axis 4, 6% of variance, DAS28 and ESR. Moderate to severe pain was significantly associated with axes 1 and 2.
Conclusions
Despite a high proportion of patients on biological treatments, 38.4% of patients continue to experience moderate to severe pain. Pain is associated with the RA activity score, but also with the depression and anxiety scores.
from Wiley: European Journal of Pain: Table of Contents https://ift.tt/31shegk
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