Pain resulting directly or indirectly from the growth of malignant cells is one of the most common and distressing symptoms associated with cancer.62 Cancer-related pain occurs in approximately one-quarter of the patients at the time of diagnosis and early in the course of disease, in three-quarters of the patients with advanced disease, and in almost one-third of the patients on active therapy.10,15,62 It is estimated that almost one in two patients with cancer pain are sub-optimally treated.10
from The Journal of Pain https://ift.tt/2CDnlSZ
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