Spinal 5-HT1AR contributes to the analgesia of acupoint catgut embedding by inhibiting phosphorylation of the NMDA receptor GluN1 subunit in CFA-induced inflammatory pain in rats

Acupuncture, which can be performed in several different ways, has been widely used for managing many diseases, including chronic inflammatory pain, especially in drug-refractory patients 3, 4, 55. Several large studies have also provided evidence that acupuncture is a relatively safe treatment 34, 47, 50.

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