Postoperative pain following bone reconstruction is one of the most frequent undesirable complications, especially in bone iliac crest graft procedures 15,24,28,36,42,54. This pain significantly disrupts patient recovery by reducing their mobility, delaying their functional recovery, increasing their hospital stay and decreasing their quality of life and autonomy 37,53. Furthermore, recent data suggest that chronic pain could induce changes at the immune system level, by modifying immune cell gene expression 29.
from The Journal of Pain https://ift.tt/2jXBik4
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