IL-18 Contributes to Bone Cancer Pain by Regulating Glia Cells and Neuron Interaction

1. IL-18 signaling plays a critical role in bone cancer-induced pain.2. IL-18 signaling could induce GluN2B activation through Src kinase during bone cancer pain.3. IL-18-mediated microglia/astrocyte and microglia/neuron interactions in the dorsal horn.

from The Journal of Pain http://ift.tt/2yN5R4q
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