Habituation (i.e., decreases in responding) and sensitization (i.e., increases in responding) following prolonged or repeated exposures to a fixed stimulus, have been identified as important in adaptation to repeated or prolonged noxious stimulation. Determinants of habituation or sensitization are poorly understood, and experimental investigation of habituation of pain ratings have generally relied on pain reports and statistical techniques that average responses across a group of participants.
from The Journal of Pain http://ift.tt/2fQymGJ
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